RESUMEN:
Objetivo: Determinar la correlación entre el valor del coeficiente de difusión aparente (ADC) de las lesiones hepáticas con los resultados finales por imagen e histopatológico. Material y métodos: Estudio no probabilístico de tipo retrospectivo, observacional y transversal, que contó con 40 pacientes en el periodo 2016-2019 en Hospital Médica Sur, se evaluó los segmentos hepáticos afectados, diagnósticos por imagen e histopatológico, se utilizó medidas de tendencia central, porcentajes, así como sensibilidad, especificidad y valores predictivos positivo y negativo. Resultados: Se analizaron 73 lesiones en 40 pacientes (21 mujeres y 19 hombres) con edad promedio de 57.9 años; 69 de las 73 tuvieron diagnóstico adecuado y solo cuatro diferente mediante biopsia. El segmento VI fue el más afectado con 17 lesiones, seguido del V y el VIII con 16 lesiones. Las lesiones con mayor valor ADC fueron el hemangioma (1,711.18 x10-6 mm2/s), hiperplasia nodular focal (1,236.3 x10-6 mm2/s) y colangitis (1,241 x10-6 mm2/s); con valores intermedios el adenoma hepático (1,140 x10-6 mm2/s); las lesiones que presentaron valores más bajos fueron el hepatocarcinoma (con valores de hasta 479 x10-6 mm2/s) y el colangiocarcinoma (772.3 x10-6 mm2/s); las metástasis presentaron valores fluctuantes desde los 800 x10-6 mm2/s hasta incluso 2,000 x10-6 mm2/s. Conclusiones: Se encontró una correlación importante del valor del ADC con el grado de malignidad de las lesiones, sin embargo las metástasis presentaron variabilidad en su valor. Los resultados son similares con la literatura actual, los resultados menores de 1,000 x10-6 mm2/s corresponden con lesiones potencialmente malignas y las que presentan un valor de ADC mayor de 1,400 x10-6 mm2/s probablemente benignas. Palabras claves: ADC. Coeficiente de difusión aparente. Lesiones hepáticas. Hepatocarcinoma. Hemangioma.

ABSTRACT:
Aim: To determine the correlation between the ADC values of liver lesions with the final results by imaging and histopathology. Material and methods: Non-probabilistic, retrospective, observational and cross-sectional study in the 2016-2019 period at Hospital Médica Sur, with 40 patients, affected liver segments. Diagnostic imaging and histopathology were evaluated, central tendency measures were used, percentages, as well as sensitivity, specificity and positive and negative predictive values. Results: 73 lesions were analyzed in 40 patients (21 women and 19 men) with an average age of 57.9 years; 69 of the 73 had an adequate diagnosis and only 4 different by biopsy. Segment VI was the most affected with 17 injuries, followed by V and VIII with 16 injuries. The lesions with the highest ADC value were hemangioma (1,711.18 x10-6 mm2/s), focal nodular hyperplasia (1,236.3 x10-6 mm2/s), and cholangitis (1,241 x10-6 mm2/s); with intermediate values liver adenoma (1,140 x10-6 mm2/s); the lesions that presented lower values were hepatocarcinoma (with values up to 479 x10-6 mm2/s), and cholangiocarcinoma (772.3 x10-6 mm2/s); the metastases showed fluctuating values from 800 x10-6 mm2/s to even 2,000 x10-6 mm2/s. Conclusions: An important correlation was found between the value of the ADC and the degree of malignancy of the lesions, however, the metastases presented variability in their value. The results are similar to the current literature, the results less than 1,000 x10-6 mm2/s correspond to potentially malignant lesions and those with an ADC value greater than 1,400 x10-6 mm2/s probably benign.

ABSTRACT:
Aim: To determine the correlation between the ADC values of liver lesions with the final results by imaging and histopathology. Material and methods: Non-probabilistic, retrospective, observational and cross-sectional study in the 2016-2019 period at Hospital Médica Sur, with 40 patients, affected liver segments. Diagnostic imaging and histopathology were evaluated, central tendency measures were used, percentages, as well as sensitivity, specificity and positive and negative predictive values. Results: 73 lesions were analyzed in 40 patients (21 women and 19 men) with an average age of 57.9 years; 69 of the 73 had an adequate diagnosis and only 4 different by biopsy. Segment VI was the most affected with 17 injuries, followed by V and VIII with 16 injuries. The lesions with the highest ADC value were hemangioma (1,711.18 x10-6 mm2/s), focal nodular hyperplasia (1,236.3 x10-6 mm2/s), and cholangitis (1,241 x10-6 mm2/s); with intermediate values liver adenoma (1,140 x10-6 mm2/s); the lesions that presented lower values were hepatocarcinoma (with values up to 479 x10-6 mm2/s), and cholangiocarcinoma (772.3 x10-6 mm2/s); the metastases showed fluctuating values from 800 x10-6 mm2/s to even 2,000 x10-6 mm2/s. Conclusions: An important correlation was found between the value of the ADC and the degree of malignancy of the lesions, however, the metastases presented variability in their value. The results are similar to the current literature, the results less than 1,000 x10-6 mm2/s correspond to potentially malignant lesions and those with an ADC value greater than 1,400 x10-6 mm2/s probably benign.