RESUMEN:
El estudio radiológico de la mama ha ido evolucionando tecnológicamente, desde las mamografías analógicas, pasando por la mamografía digital indirecta, hasta las mamografías digitales de campo completo (M2D). Uno de los últimos avances ha sido la tomosíntesis (TS), una técnica que genera una mamografía casi tridimensional que disminuye la superposición de tejido fibroglandular y ha demostrado un aumento en la detección de cánceres, por lo que se está convirtiendo en el estándar en programas de cribado y diagnóstico a nivel mundial. Dado que inicialmente la FDA aprobó su uso junto a la mamografía M2D, se generó un aumento en la radiación recibida por la paciente, aunque siempre debajo del límite establecido de 3 mGy por exposición. Para resolver este problema se desarrolla la mamografía sintetizada (MS), en la que se obtiene una mamografía a partir de la TS, eliminando la necesidad de realizar una M2D y disminuyendo la radiación a aproximadamente la mitad. El objetivo del presente artículo de revisión es repasar las características técnicas de la MS y mostrar la evidencia publicada, respondiendo preguntas frecuentes.

Abstract:
Mammographic screening techniques have continued to evolve along technology, from analogic to full field digital mammograms (FFDM). One of the latest advances is digital breast tomosynthesis (DBT), a quasi-tridimensional mammogram that decreases the overlapping effect of the tissue and improves cancer detection, emerging as the standard of care in the screening and diagnostic setting. Initially, FDA approval of DBT specified its performance in conjunction with FFDM, which approximately doubles the dose of the 2D FFDM exam alone, while still below radiation safety limit of 3 mGy per view. Synthetized mammography (s2D) was developed in response to this challenge. It is created from the DBT data set, obviating the need of a conventional FFDM thus reducing radiation dose by half. The objective of this article is to review the technical aspects of the s2D and summarize published evidence, answering frequent asked questions.

Abstract:
Mammographic screening techniques have continued to evolve along technology, from analogic to full field digital mammograms (FFDM). One of the latest advances is digital breast tomosynthesis (DBT), a quasi-tridimensional mammogram that decreases the overlapping effect of the tissue and improves cancer detection, emerging as the standard of care in the screening and diagnostic setting. Initially, FDA approval of DBT specified its performance in conjunction with FFDM, which approximately doubles the dose of the 2D FFDM exam alone, while still below radiation safety limit of 3 mGy per view. Synthetized mammography (s2D) was developed in response to this challenge. It is created from the DBT data set, obviating the need of a conventional FFDM thus reducing radiation dose by half. The objective of this article is to review the technical aspects of the s2D and summarize published evidence, answering frequent asked questions.